The Normal Heart, Left Ventricular Hypertrophy in Hypertension, and Heart Failure in Hypertension
This three-part animation sequence is available for your own education or the education of others. It can be viewed online using the RealOne player or downloaded to your computer for viewing with the QuickTime or Windows Media player. For viewing and downloading instructions see How to Use the Animations. Downloadable transcripts (PDF) are also available.
The Normal Heart sequence provides an overview of normal cardiac structure and physiology, along with a review of the process of excitation contraction coupling in the heart.
In the Left Ventricular Hypertrophy in Hypertension sequence abnormalities in excitation contraction coupling associated with decreased activation of the actin and myosin cross-bridges are reviewed. These abnormalities are believed to set the stage for the transition from concentric hypertrophy to dilated cardiomyopathy.
The Heart Failure in Hypertension sequence details the abnormalities in myocyte shortening that are believed to contribute importantly to the
development of left ventricular systolic dysfunction in the failing heart.
| Online Animation |
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Large Presentation
View this presentation if you have a broadband connection to the Internet (DSL, cable modem, corporate/campus network). RealOne from Real is required to view this video. |
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Small Presentation
View this presentation if you are accessing the Internet with a 56k modem or if your network does not support large files. RealOne from Real is required to view this video. |
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Downloadable Animations
The files below are available for you to download
to your computer for off-line educational or personal use.
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| Downloadable Files (Right-click to download. For help, see downloading instructions below.) |
| Part I: The Normal Heart |
QuickTime |
Windows Media |
| Large - 320 pixels x 240 pixels |
 (5.4 Mb) |
 (6.2 Mb) |
| Small - 200 pixels x 148 pixels |
(3.4 Mb) |
(1.6 Mb) |
| Part II: Left Ventricular Hypertrophy in Hypertension |
| Large - 320 pixels x 240 pixels |
(3.5 Mb) |
(6.2 Mb) |
| Small - 200 pixels x 148 pixels |
(2.7 Mb) |
(1.3 Mb) |
| Part III: Heart Failure in Hypertension |
| Large - 320 pixels x 240 pixels |
(3.4 Mb) |
(5.9 Mb) |
| Small - 200 pixels x 148 pixels |
(2.6 Mb) |
(1.3 Mb) |
| Animation Transcripts |
Adobe PDF Files |
| Entire Sequence: The Normal Heart, Left Ventricular Hypertrophy in Hypertension and Heart Failure in Hypertension |
 (70 Kb) |
| Part I: The Normal Heart |
(63 Kb) |
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| Part II: Left Ventricular Hypertrophy in Hypertension |
(60 Kb) |
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| Part III: Heart Failure in Hypertension |
(59 Kb) |
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Instructions for Downloading the Animation Files:
- Right click (cntrl-click on Mac) on the or icon.
- Select 'Save Target As' from the pop-up menu.
- Save the file onto your desktop.
- Locate the file on your desktop and open it by double clicking.
For more detailed information, please see How
to Use the Animations.
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